In estrogen treated ovariectomized and pregnant mice on the first day after mating
a sixth LDH isozyme appeared at Relative mobility (Rm) 0.08 to 0.15 and for convenience
this isozyme is provisionally designated as LDH-Y. The appearance of a sixth LDH isozyme
(LDH-Y) in mice uterus after ovariectomy and estrogen treatment favours the idea that
this isozyme is estrogen dependent. Presence of this LDH-Y in mice uterus during preimplantation
and finally its sudden disappearance during implantation and post implantation periods
further suggest that LDH-Y is estrogen dependent and responsible for restoring fertility
in mice.
LDH-Y Isozyme - Estrogen and Fertility
